Day 1 (APR 5): Fort Lauderdale, Florida

Departs @ 5:00pm

Days 2-3 (APR 6-7): Days at Sea

Day 4 (APR 8): Cartagena, Colombia

A visit to Cartagena, Colombia, promises well-preserved colonial architecture, flavorful cuisine, and the legacy of Nobel laureate Gabriel García Márquez. Holland America Line’s excursions offer a gateway to this historical and culinary gem, where the past and present blend seamlessly. Wander through the streets of this walled city, tasting local delicacies, exploring Castillo San Felipe de Barajas, and enjoying the vestiges of its rich literary past.

Day 5 (APR 9): Cruising Panama Canal

The construction of the Panama Canal is one of those epic tales from the past, an old-school feat of engineering, ambition and courage. A cruise along it today is a journey through the centuries, from the Spanish fortifications near Limón Bay to the glittering skyline of Panama City, not to mention the canal itself.

Day 6 (APR 10): Day at Sea

Day 7 (APR 11): Puntarenas, Costa Rica

One of the stops along the Panama Canal Zone route, Puntarenas on Costa Rica's Pacific Coast is nicely positioned within easy day-trip distance of a number of that country's national parks. The town, a busy working port on the surface, makes an ideal base from which travelers can venture out to explore the variety of this Central American country's outdoor attractions, from lush jungle destinations to pristine beaches along the Pacific. Activities include snapping photos of gushing waterfalls (and swimming at the base of one, if you bring your swimsuit!), sightseeing near active volcanoes, bird-watching in nature reserves and sanctuaries and horseback riding on Pacific beaches . . . and that's just for starters. Visitors to this extraordinary region also enjoy shopping for the handicrafts that local artists sell at their cooperatives, as well as sampling traditional Tico cuisine, especially gallo pinto—a combination of rice and beans eaten at any time of the day or night.

Day 8 (APR 12): Day at Sea

Day 9 (APR 13): Acajutla, El Salvador

Stunning beaches and colorful markets await on cruises to Acajutla, El Salvador. As the ship approaches, breathtaking views of the serene coastline greet your gaze. For such a small town, Acajutla has an array of things to do. Taxis offer the optimal way to travel from the port. Sightseeing is a breeze, as top attractions are only an hour away. Explore the historical city center, known for its charming streets and friendly locals. Stretch out on Acajutla Beach, a short shuttle from the cruise port. Dive vibrant reefs, tour Mayan ruins, or learn how coffee — one of the country’s main exports — is produced at a roastery.

Day 20 (APR 14): Puerto Quetzal, Guatemala

Puerto Quetzal is Guatemala's largest port on the Pacific Ocean side of this Central American country, important for both cargo and cruise ships. There's not a great deal to see and do in Puerto Quetzal itself, and visitors should adjust their expectations accordingly. Yet you shouldn't despair, either; Puerto Quetzal is an ideal point of departure for exploring several corners of the country. Choose your mode of transportation—plane, bus, car or boat—and decide whether you want to take in Guatemala's stunning, volcano-studded landscape, one (or more!) of the country's Maya sites, the UNESCO–recognized colonial city of Antigua (the former capital), a coffee plantation or one of the many beguiling bodies of water. In addition to the gleaming Pacific, there's Lake Atitlán, which 19th-century German explorer Alexander von Humboldt described as the most beautiful lake in the world. All of these attractions are accessible as day trips, and getting to them is all part of your Guatemalan adventure.

Days 11-12 (APR 15-16): Days at Sea

Day 13 (APR 17): Puerto Vallarta, Mexico

Cruise to Puerto Vallarta and find yourself immersed in dynamic culture and history. Unlike other coastal resort towns in Mexico, Puerto Vallarta ("PV" to locals), retains quite a bit of its colonial-era charm. While on your Puerto Vallarta cruise, take in these echoes of the past and more modern attractions, including an ambitious public art project along the seaside walkway (the malecón) and trendy restaurants such as La Leche, serving contemporary Mexican cuisine. Round these out with plenty of fun-in-the-sun outdoor activities on and along Banderas Bay (whale-watching! snorkeling! jet-skiing!), cruise excursions that reveal the best of Puerto Vallarta's flora and fauna, and a side trip to one of Mexico's pueblos mágicos (magical towns, a designation conferred by the government to recognize smaller towns that possess historical and cultural value), and you'd be hard-pressed to find a more pleasant place to spend part of your cruise to Puerto Vallarta.

Day 14 (APR 18): Cabo San Lucas, Mexico

Los Cabos—or the Capes—sits at the southernmost tip of the Baja California Peninsula, a narrow strip of land whose varied geography makes for plenty of interesting and unusual activities. You can ride a camel, or enjoy more predictable pursuits including fishing, golfing and whale-watching. On your Cabo cruise you can visit picture-perfect El Arco, an arch that may look familiar thanks to its cameo on postcards and advertisements. North of the capes, you can drop by the famed Hotel California. And if you've worked up an appetite on your Cabo cruise, you won't be disappointed: Los Cabos offers plenty to enjoy at the table as well, with farm-fresh fruits and vegetables and, of course, seafood being the mainstays here. Regardless, Holland America Line makes sure that Cabo cruises have plenty of new and traditional things for guests to experience.

Day 15 (APR 19): Day at Sea

Day 16 (APR 20): San Diego, California

With more than 300 days of sun every year, renowned surf spots like Del Mar and La Jolla, and a bustling culinary and craft beer scene, San Diego is a surfer's paradise and a feast for foodies. Explore distinct neighborhoods and enjoy the city’s laid-back charm on cruises to San Diego, California.

Day 17 (APR 21): Avalon, California

You can easily explore Avalon in a few hours, as nearly everything is concentrated in a few blocks. That leaves the afternoon for exploring the rest of the island.

Days 18-19 (APR 22-23): Days at Sea

Day 20 (APR 24): Vancouver, B.C.

The perfect combination of urban meets nature, Vancouver is a hub for lovers of the great outdoors. Enjoy picturesque views of the mountains while exploring the city’s local hot spots like Stanley Park, Granville Island, Gastown and more. Don’t forget to sample the best of the local culinary and cocktail scene for something truly unique.

Day 21 (APR 25): Seattle, Washington

Arrives @ 7:00am